HIF1A-AS2 Regulates Hypoxia-Driven HIF Isoform Switching in Human Endothelial Cells
A. Barton, A. Wiech-Walow, P. Czechowicz, A. Cabaj, L. Schaefer, J. F. Collawn, Rafal Bartoszewski
This study shows HIF1A-AS2 regulates the switch from HIF-1 to HIF-2 signaling in hypoxia by reducing HIF1A expression and increasing HIF-2 activity in endothelial cells.
bioRxiv · Nov 9, 2026 · PreprintMolecular Biology