Serotonin, Etonogestrel and breathing activity in murine Congenital Central Hypoventilation Syndrome
A. Casciato, L. Bianchi, F. Joubert, R. Delucenay-Clarke, S. Parrot, N. Ramanantsoa, E. Sizun, B. Matrot, C. Straus, T. Similowski, F. Cayetanot, L. Bodineau
This study investigates whether etonogestrel restores chemosensitivity in Phox2b mutant mice by acting on serotonin neurons or residual PHOX2B cells, finding it primarily affects serotonin systems.
bioRxiv · Apr 19, 2022Physiology