Activation of cGAS/STING pathway upon paramyxovirus infection
M. Iampietro, C. Dumont, C. Mathieu, J. Spanier, J. Robert, A. Charpenay, S. Dupichaud, K. P. Dhondt, N. Aurine, R. Pelissier, M. Ferren, S. Mely, D. Gerlier, U. Kalinke, B. Horvat
This study shows that paramyxoviruses like NiV and MeV activate the cGAS/STING pathway, leading to type-I interferon production and host protection against infection.
bioRxiv · Dec 26, 2020Immunology