Fractionated brain irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior and cognition in mice
L. Kuil, R. Seigers, M. Loos, M. C. de Gooijer, A. Compter, W. Boogerd, O. van Tellingen, A. B. Smit, S. B. Schagen
This study shows that fractionated brain irradiation reduces hippocampal immature neurons in mice but does not affect spontaneous behavior or traditional cognitive tasks.
bioRxiv · Sep 1, 2022 · PreprintAnimal Behavior & Cognition