Effects of sexual dimorphism and estrous cycle on murine Clostridioides difficile infection
J. R. Phan, E. Bacab, M. Washington, M. Niamba, D. M. Do, T. V. Mata, A. Consul, L. Blank, S. Yang, A. J. Howerton, E. Heredia, R. Soriano, C. Hassan, C. L. Cross, E. Abel-Santos
This study shows female mice develop more severe Clostridioides difficile infection than males, with estrous cycle phase influencing disease severity and immune response networks.
bioRxiv · Jul 5, 2023Microbiology