Author

J. R. Phan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Assay:metagenomics· 2 Organism:mouse· 2 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

E. Abel-Santos· 3 shared B. P. Hedlund· 2 shared C. C. Mefferd· 2 shared D. M. Do· 2 shared J. V. Villarama· 2 shared S. Alarcia· 2 shared A. Consul· 1 shared A. E. Fox-King· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMicrobiology

E. Abel-Santos

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Effects of sexual dimorphism and estrous cycle on murine Clostridioides difficile infection

J. R. Phan, E. Bacab, M. Washington, M. Niamba, D. M. Do, T. V. Mata, A. Consul, L. Blank, S. Yang, A. J. Howerton, E. Heredia, R. Soriano, C. Hassan, C. L. Cross, E. Abel-Santos

This study shows female mice develop more severe Clostridioides difficile infection than males, with estrous cycle phase influencing disease severity and immune response networks.

bioRxiv · Jul 5, 2023Microbiology

A high-carbohydrate diet prolongs dysbiosis and Clostridioides difficile carriage and increases late-onset CDI and mortality in a hamster model of infection

S. Bhute, C. C. Mefferd, J. R. Phan, M. Ahmed, A. E. Fox-King, S. Alarcia, J. V. Villarama, E. Abel-Santos, B. P. Hedlund

This study shows a high-carbohydrate diet worsens Clostridioides difficile infection in hamsters by causing prolonged dysbiosis, persistent carriage, and higher mortality compared to a standard diet.

bioRxiv · Oct 4, 2021 · PreprintMicrobiology

A high-fat/high-protein, Atkins-type diet exacerbates Clostridioides (Clostridium) difficile infection in mice, whereas a high-carbohydrate diet protects

C. C. Mefferd, S. S. Bhute, J. R. Phan, J. V. Villarama, D. M. Do, S. Alarcia, E. Abel-Santos, B. P. Hedlund

This study shows that a high-fat/high-protein diet worsens C. difficile infection in mice, while a high-carbohydrate diet protects against it.

mSystems · Feb 11, 2020Peer-reviewedMicrobiology