Broad-spectrum, patient-adaptable inhaled niclosamide-lysozyme particles are efficacious against coronaviruses in lethal murine infection models
A. D. Brunaugh, H. Seo, Z. Warnken, L. Ding, S. H. Seo, H. D. C. Smyth
This paper develops an inhaled niclosamide-lysozyme formulation effective against coronaviruses in mice, showing potent in vitro and in vivo activity against MERS-CoV and SARS-CoV-2.
bioRxiv · Sep 24, 2020 · PreprintPharmacology & Toxicology