Anticancer Drug Impact on DNA - A Study by Neutron Spectrocopy, Synchrotron-based FTIR and EXAFS
A. L. M. Batista de Carvalho, A. P. Mamede, A. Dopplapudi, V. Garcia Sakai, J. Doherty, M. Frogley, G. Cinque, P. Gardner, D. Gianolio, L. A. E. Batista de Carvalho, M. P. M. Marques
This study uses neutron spectroscopy, synchrotron-based FTIR, and EXAFS to analyze how Pt/Pd drugs interact with DNA, revealing structural and dynamic changes linked to their cytotoxic effects.
bioRxiv · Aug 23, 2018Biophysics