Antigen-driven CD8+ T cell clonal expansion is a prominent feature of MASH in humans and mice.
A. E. Burtis, D. M. DeNicola, M. E. Ferguson, R. G. Santos, C. Pinilla, M. S. Kriss, D. J. Orlicky, B. A. J. Tamburini, A. E. Gillen, M. A. Burchill
This study identifies antigen-driven CD8+ T cell clonal expansion in human and mouse MASH, showing their activation and functional differentiation in liver disease.
bioRxiv · Mar 20, 2024 · PreprintImmunology