Pan-cancer Analysis of Homologous Recombination Deficiency in Cell Lines
A. E. Dodson, S. Shenker, P. Sullivan, C. Middleton, M. McGuire, E. Chipumuro, Y. Mishina, E. Tobin, L. Cadzow, A. A. Wylie, D. Sangurdekar
This study predicts HRD in 1,332 cancer and 84 non-cancer cell lines using CHORD and HRDsum, finding BRCA1/2 mutations and epigenetic silencing as key predictors.
Cancer Research Communications · Dec 6, 2024Peer-reviewedCancer Biology