Dectin-1 Molecular Aggregation and Signaling is Sensitive to β-Glucan Structure and Glucan Exposure on Candida albicans Cell Walls
E. U. Anaya, A. Etemadi Amin, M. J. Wester, M. Danielson, K. Michel, A. K. Neumann
This study shows that Dectin-1A signaling and molecular aggregation depend on β-glucan structure and exposure, with higher structured glucans inducing more receptor dimerization and signaling.
bioRxiv · May 25, 2020 · PreprintImmunology