A new insight into MYC action: control of RNA polymerase II methylation and transcription termination
F. Scagnoli, A. Palma, A. Favia, C. Scuoppo, B. Illi, S. Nasi
This study shows MYC regulates RNA polymerase II methylation and transcription termination through interaction with PRMT5, and its inhibition affects gene expression in cancer cells.
bioRxiv · Feb 17, 2022Cancer Biology