Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells
G. Moenke, E. Christiano, A. Finzel, D. Friedrich, H. Herzel, M. Falcke, A. Loewer
The paper studies p53 network dynamics in single cells, showing excitable behavior with tunable activation thresholds and heterogeneity in response due to Wip1 levels.
bioRxiv · Aug 9, 2016Cell Biology