Author

D. Friedrich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. Falcke· 2 shared A. DePace· 1 shared A. Finzel· 1 shared A. Haribabu· 1 shared A. Loewer· 1 shared C. Fink· 1 shared D. G. Tenen· 1 shared D. Tenen· 1 shared

Activity by Year

2016-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

M. Falcke

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Emergence of activation or repression in transcriptional control under a fixed molecular context

R. Martinez-Corral, D. Friedrich, R. Fromel, L. Velten, J. Gunawardena, A. DePace

This study uses biophysical models to show that transcription factors can act as activators, repressors, or both, with their effects influenced by binding affinity and regulatory context.

bioRxiv · May 29, 2024Biophysics

Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies

J. Hüttemeister, F. Rudolph, M. Radke, C. Fink, D. Friedrich, S. Preibisch, M. Falcke, E. Wagner, S. E. Lehnart, M. Gotthardt

This study uses mCherry-titin mice to visualize sarcomere dynamics during skeletal muscle development and injury repair, revealing titin mobility and localization patterns in myocytes.

bioRxiv · Feb 1, 2024 · PreprintCell Biology

C/EBPα acts as an RNA binding protein essential for its chromatin recruitment and promotes Macrophage differentiation

Y. Zhang, M. Bassal, D. Friedrich, S. Ummarino, T. Verbiest, J. Zhang, D. Tenen, A. Haribabu, D. G. Tenen

The paper shows C/EBPα binds RNA via novel domains, recruits to enhancer sites, and promotes Macrophage differentiation by regulating PU.1 expression.

bioRxiv · Oct 20, 2021 · PreprintCell Biology

Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells

G. Moenke, E. Christiano, A. Finzel, D. Friedrich, H. Herzel, M. Falcke, A. Loewer

The paper studies p53 network dynamics in single cells, showing excitable behavior with tunable activation thresholds and heterogeneity in response due to Wip1 levels.

bioRxiv · Aug 9, 2016Cell Biology