Antimicrobial activity of Mycobacteriophage D29 Lysin B during Mycobacterium ulcerans infection
A. G. Fraga, G. Trigo, J. Dominguez, R. Silva-Gomes, C. M. Goncalves, H. Oliveira, A. G. Castro, J. Azeredo, J. Pedrosa
This study shows that recombinant Lys B, a phage-encoded enzyme, reduces M. ulcerans bacterial burdens in mice and induces immune responses, suggesting its potential as a new therapeutic for Buruli Ulcer.
bioRxiv · Dec 27, 2018Microbiology