Functional modulation of T follicular cells in vivo enhances antigen-specific humoral immunity
J. Pagan, H. Vlakamis, A. Gaca, R. Xavier, R. Anthony
The paper shows that reducing TFR influence through antibiotic treatment or PD-1 blockade enhances antigen-specific IgG affinity and TFH cell numbers in mice.
bioRxiv · Nov 17, 2020Immunology