CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev
F. Garcia-de-Gracia, D. Toro-Ascuy, S. Riquelme-Barrios, C. Pereira-Montecinos, B. Rojas-Araya, A. Gaete-Argel, M. L. Acevedo, J. Chnaiderman, F. Valiente-Echeverria, R. Soto-Rifo
The paper shows CTIF inhibits HIV-1 Gag synthesis by blocking Rev function through mRNA ribonucleoprotein complex association and cytoplasmic Rev accumulation.
bioRxiv · Jul 22, 2019Microbiology