In-vivo subdermal implant in the alpha-Gal knockout mice model for the assessment of bioprosthetic heart valve calcification rate before and after a polyphenols-based treatment
F. Naso, A. Colli, P. Zilla, A. M. Calafiore, C. Lotan, M. Padalino, G. Sturaro, A. Gandaglia, M. Spina
This study evaluates the calcification rate of bioprosthetic heart valves in a humanized Gal knockout mouse model before and after polyphenol treatment, showing significant inhibition of calcium deposition.
bioRxiv · Feb 21, 2023 · PreprintBioengineering