NAD+ prevents septic shock-induced death by non-canonical inflammasome blockade and IL-10 cytokine production in macrophages
J. Iske, R. El Fatimy, Y. Nian, A. Ghouzlani, S. Eskandari, H. R. Cetina Biefer, A. Vasudevan, A. Elkhal
This study shows NAD+ prevents septic shock by blocking non-canonical inflammasome activation and promoting IL-10 cytokine production in macrophages.
bioRxiv · Mar 29, 2020Immunology