Deleting in vivo β-catenin degradation domain in mouse hepatocytes drives hepatocellular carcinoma or hepatoblastoma-like tumors
R. Loesch, S. Caruso, V. Paradis, C. Godard, A. Gougelet, S. Picard, C. Perret, M. M. M. Taketo, J. Zucman-Rossi, S. Colnot
This study compares two mouse models of β-catenin pathway activation, showing they generate tumors similar to human hepatocellular carcinomas and hepatoblastomas.
bioRxiv · Jul 4, 2021 · PreprintCancer Biology