Author

J. Zucman-Rossi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. Caruso· 3 shared A. Camasses· 1 shared A. Gougelet· 1 shared A. Loriot· 1 shared A. Lozano· 1 shared C. Gerard· 1 shared C. Godard· 1 shared C. Perret· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCancer Biology

S. Caruso

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Author profile →

3 papers

Recent·Most cited

Deleting in vivo β-catenin degradation domain in mouse hepatocytes drives hepatocellular carcinoma or hepatoblastoma-like tumors

R. Loesch, S. Caruso, V. Paradis, C. Godard, A. Gougelet, S. Picard, C. Perret, M. M. M. Taketo, J. Zucman-Rossi, S. Colnot

This study compares two mouse models of β-catenin pathway activation, showing they generate tumors similar to human hepatocellular carcinomas and hepatoblastomas.

bioRxiv · Jul 4, 2021 · PreprintCancer Biology

CDK8 and CDK19 kinases have non-redundant oncogenic functions in hepatocellular carcinoma

K. Bacevic, S. Prieto, S. Caruso, A. Camasses, G. Dubra, J. Ursic-Bedoya, A. Lozano, J. Butterworth, J. Zucman-rossi, U. Hibner, D. Fisher, D. Gregoire

The paper investigates the roles of CDK8 and CDK19 in hepatocellular carcinoma, finding they are overexpressed and have non-redundant oncogenic functions that interact with TP53.

bioRxiv · Oct 1, 2019 · PreprintCancer Biology

Dynamics and predicted drug response of a gene network linking dedifferentiation with beta-catenin dysfunction in hepatocellular carcinoma

C. Gerard, M. Di-Luoffo, L. Gonay, S. Caruso, G. Couchy, A. Loriot, J. Tao, K. Konobrocka, S. Cordi, S. P. Monga, E. Hanert, J. Zucman-Rossi, F. P. Lemaigre

The paper identifies and models a gene regulatory network linking LIN28B-dependent dedifferentiation with CTNNB1 dysfunction in HCC, predicting drug response and cell state dynamics.

bioRxiv · Jun 15, 2018Cancer Biology