HPLC Method to Resolve, Identify and Quantify Guanine Nucleotides Bound to the GTPase Ras
J. P. Hannan, G. H. Swisher, J. G. Martyr, N. J. Cordaro, A. H. Erbse, J. J. Falke
The paper describes an HPLC method to resolve, identify, and quantify guanine nucleotides bound to Ras, enabling analysis of fractional activation and providing insights into Ras mutation mechanisms.
bioRxiv · Jun 28, 2021Cancer Biology