Author

J. J. Falke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. H. Erbse· 1 shared B. P. Ziemba· 1 shared G. H. Swisher· 1 shared J. G. Martyr· 1 shared J. P. Hannan· 1 shared M. T. Gordon· 1 shared N. J. Cordaro· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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1 shared paperCancer Biology

A. H. Erbse

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2 papers

Recent·Most cited

Single Molecule Studies Reveal Regulatory Interactions between Master Kinases PDK1, AKT1 and PKCalpha

M. T. Gordon, B. P. Ziemba, J. J. Falke

This paper uses single molecule studies to show that PDK1 forms heterodimers with AKT1 and PKC on membranes, with PKC displacing AKT1 and inhibiting its activation, suggesting a tumor suppressor role for PKC.

Biophysical Journal · Dec 1, 2021Peer-reviewedBiophysics

HPLC Method to Resolve, Identify and Quantify Guanine Nucleotides Bound to the GTPase Ras

J. P. Hannan, G. H. Swisher, J. G. Martyr, N. J. Cordaro, A. H. Erbse, J. J. Falke

The paper describes an HPLC method to resolve, identify, and quantify guanine nucleotides bound to Ras, enabling analysis of fractional activation and providing insights into Ras mutation mechanisms.

bioRxiv · Jun 28, 2021Cancer Biology