Single-molecule live cell imaging of Rep reveals the dynamic interplay between an accessory replicative helicase and the replisome
A. Syeda, A. Wollman, A. Harvgreaves, J. Bruning, P. McGlynn, M. Leake
The paper uses single-molecule live cell imaging to study the dynamic interactions of the bacterial helicase Rep with the replisome and PriC, revealing two distinct mechanisms for overcoming nucleoprotein barriers during DNA replication.
bioRxiv · Sep 29, 2018Biophysics