Regulation of nuclear actin levels and MRTF/SRF target gene expression during PC6.3 cell differentiation
S. Kyheroinen, A. Hyrskyluoto, M. Sokolova, M. K. Vartiainen
This study shows that nuclear actin levels increase during PC6.3 cell differentiation, leading to reduced MRTF-A nuclear localization and downregulation of MRTF/SRF target genes.
bioRxiv · Jun 14, 2022Cell Biology