The structure, catalytic mechanism, and inhibitor identification of phosphatidylinositol remodeling MBOAT7
K. Wang, C.-W. Lee, X. Sui, S. Kim, S. Wang, A. B. Higgs, A. J. Baublis, G. A. Voth, M. Liao, T. C. Walther, R. V. Farese
This study determines the structure of MBOAT7, models its catalytic mechanism, and identifies potential inhibitors for therapeutic development.
bioRxiv · Sep 15, 2022 · PreprintBiochemistry