A. J. Henderson

Intragenic proviral elements support transcription of defective HIV-1 proviruses

The paper shows defective HIV-1 proviruses can be transcribed via intragenic elements, producing aberrant RNAs that may contribute to inflammation in HIV-positive individuals.

Strength of T cell signaling regulates HIV-1 replication and establishment of latency

This study shows that strong T cell signaling promotes HIV-1 expression and inducible latency, while weak signaling leads to stable, refractory latency.