Surface condensation of a pioneer transcription factor on DNA
J. A. Morin, S. Wittmann, S. Choubey, A. Klosin, S. Golfier, A. A. Hyman, F. Julicher, S. W. Grill
This study uses optical tweezers to observe Klf4 condensation on DNA, showing surface-mediated microphases that reconcile phase separation with nuclear organization.
bioRxiv · Sep 24, 2020 · PreprintBiophysics