First crystal structure of double knotted protein TrmD-Tm1570 - inside from degradation perspective
F. Bruno da Silva, I. Lewandowska, A. Kluza, S. Niewieczerzal, R. Augustyniak, J. I. Sulkowska
The paper presents the first crystal structure of a double knotted protein TrmD-Tm1570 and shows it can be degraded by the ClpXP system, with simulations explaining degradation kinetics.
bioRxiv · Mar 13, 2023 · PreprintBiophysics