Cytotoxic efficiency of human CD8+ T cell memory subtypes
A. Knörck, G. Schwär, D. Alansary, L. Thurner, M. Hoth, E. C. Schwarz
This study quantifies the cytotoxic efficiency of human TEM and TCM CD8+ T cell subtypes, finding TEM cells are more effective in inducing apoptosis and necrosis due to higher perforin expression and more efficient lytic synapses.
bioRxiv · Mar 15, 2021Immunology