Hypothalamic hormone deficiency enables physiological anorexia
S. M. Mohr, R. D. Pra, M. P. Platt, V. V. Feketa, M. Shanabrough, L. Varela, A. Kristant, H. Cao, D. K. Merriman, T. L. Horvath, S. N. Bagriantsev, E. O. Gracheva
This study shows that thyroid hormone deficiency causes anorexia during hibernation in ground squirrels by inhibiting hypothalamic feeding center sensitivity to hunger signals.
bioRxiv · Mar 15, 2023 · PreprintPhysiology