Author

A. L. Cohen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 2

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Research Focus:clustering· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

, I. Makhoul· 1 shared A. Bardia· 1 shared A. Bild· 1 shared A. Farrell· 1 shared A. H. Bild· 1 shared A. O'Dea· 1 shared C. Ma· 1 shared D. F. Jenkins· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

, I. Makhoul

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Author profile →

2 papers

Recent·Most cited

Novel temporal and spatial patterns of metastatic colonization from rapid-autopsy tumor biopsies

X. Huang, Y. Qiao, S. W. Brady, R. E. Factor, E. Downs-Kelly, A. Farrell, J. A. McQuerry, G. Shrestha, D. F. Jenkins, W. E. Johnson, A. L. Cohen, A. H. Bild, G. T. Marth

This study uses rapid autopsy and whole genome sequencing to analyze metastatic evolution in a patient, identifying subclone incubators and four waves of metastatic expansion.

bioRxiv · Jun 3, 2021Cancer Biology

Convergent evolution of resistance pathways during early stage breast cancer treatment with combination cell cycle (CDK) and endocrine inhibitors

J. I. Griffiths, J. Chen, P. A. Cosgrove, A. O'Dea, P. Sharma, C. Ma, M. Trivedi, K. Kalinsky, K. B. Wisinski, R. O'Regan, , I. Makhoul, L. M. Spring, A. Bardia, F. R. Adler, A. L. Cohen, , A. Bild

This study examines how breast cancer tumors evolve during early stage treatment with combination CDK and endocrine inhibitors, finding convergent resistance pathways and increased subclonal diversity with combination therapy.

bioRxiv · Jan 19, 2021 · PreprintCancer Biology