Author

G. T. Marth

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Approach:deep learning· 1

Frequent Co-Authors

X. Huang· 3 shared Y. Qiao· 3 shared A. Farrell· 2 shared R. E. Factor· 2 shared A. C. Beck· 1 shared A. H. Bild· 1 shared A. J. Butterfield· 1 shared A. L. Cohen· 1 shared

Activity by Year

2021-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

X. Huang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel temporal and spatial patterns of metastatic colonization from rapid-autopsy tumor biopsies

X. Huang, Y. Qiao, S. W. Brady, R. E. Factor, E. Downs-Kelly, A. Farrell, J. A. McQuerry, G. Shrestha, D. F. Jenkins, W. E. Johnson, A. L. Cohen, A. H. Bild, G. T. Marth

This study uses rapid autopsy and whole genome sequencing to analyze metastatic evolution in a patient, identifying subclone incubators and four waves of metastatic expansion.

bioRxiv · Jun 3, 2021Cancer Biology

OncoGEMINI: Software for Investigating Tumor Variants From Multiple Biopsies With Integrated Cancer Annotations

T. J. Nicholas, M. J. Cormier, X. Huang, Y. Qiao, G. T. Marth, A. Quinlan

OncoGEMINI is a software tool that helps analyze tumor variants from multiple biopsies and integrates cancer annotations to identify mutations driving subclonal evolution.

Genome Medicine · Mar 26, 2021Peer-reviewedCancer Biology

The extracellular milieu of Toxoplasma-s lytic cycle drives lab-adaptation and promotes changes in lipid metabolism primarily driven by transcriptional reprogramming

V. A. Primo, Y. Rezvani, A. Farrell, A. Vajdi Hoojghan, G. T. Marth, K. Zarringhalam, M.-J. Gubbels

This study uses evolve and resequence to identify genetic changes in Toxoplasma gondii during lab-adaptation, revealing transcriptional reprogramming and lipid metabolism shifts.

bioRxiv · Mar 9, 2021 · PreprintMicrobiology

A breast cancer patient-derived xenograft and organoid platform for drug discovery and precision oncology

K. P. Guillen, M. Fujita, A. J. Butterfield, S. D. Scherer, M. H. Bailey, Z. Chu, Y. S. DeRose, L. Zhao, E. Cortes-Sanchez, C.-H. Yang, J. Toner, G. Wang, Y. Qiao, X. Huang, J. A. Greenland, , A. L. Welm

The paper develops patient-derived xenografts and organoids for breast cancer to enable drug screening and precision oncology, showing efficacy of an FDA-approved drug in a clinical case.

bioRxiv · Feb 28, 2021 · PreprintCancer Biology