APP and its intracellular domain modulate Alzheimers disease risk gene networks in transgenic APPsw and PSEN1M146I porcine models
M. Habekost, E. Poulsen, J. J. Enghild, M. Denham, A. L. Joergensen, P. Qvist
This study uses transgenic porcine models to show that APP and its AICD domain modulate AD-related gene networks through interactions with signaling proteins.
bioRxiv · Mar 21, 2024 · PreprintCell Biology