Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29 and Fam21
M. Romano-Moreno, E. N. Astorga-Simon, A. L. Rojas, A. Hierro
The paper identifies two Fam21 fragments interacting with VPS35 and a third interacting with VPS29, revealing distinct binding modes and structural insights into retromer-WASH complex recruitment.
bioRxiv · Jan 22, 2024Biochemistry