Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells
A. B. Justino, R. M. Florentino, A. Franca, A. C. M. L. Filho, R. R. Franco, A. L. Saraiva, M. C. Fonseca, M. F. Leite, F. Salmen Espindola
This study identifies an alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel that inhibits HepG2 cell proliferation and migration by modulating PCNA, EGFR, and intracellular calcium.
bioRxiv · Apr 7, 2021Biochemistry