Loss of self-tolerance leads to altered gene expression and IMD pathway activation in Drosophila melanogaster
P. Kr, A. L. Waring-Sparks, N. M. Bretz, N. T. Mortimer
The paper identifies deregulated transcripts and NFκB signaling in Drosophila melanogaster with loss of self-tolerance, revealing transcriptional and physiological changes associated with autoimmunity.
bioRxiv · Nov 19, 2021 · PreprintImmunology