N. T. Mortimer

Host JAK/Stat activity is a target of endoparasitoid wasp virulence strategies

This paper shows parasitoid wasps suppress Drosophila JAK-STAT pathway activity to evade immune defenses.

Loss of self-tolerance leads to altered gene expression and IMD pathway activation in Drosophila melanogaster

The paper identifies deregulated transcripts and NFκB signaling in Drosophila melanogaster with loss of self-tolerance, revealing transcriptional and physiological changes associated with autoimmunity.

Redox-mediated inactivation of the transcriptional repressor C3600 makes uropathogenic Escherichia coli exquisitely resistant to reactive chlorine species

This study identifies a redox-mediated mechanism in UPEC that enhances resistance to HOCl by inactivating the transcriptional repressor C3600 through disulfide bond formation.

Parasitoid wasp venom targets host immune cell production in a Drosophila-parasitoid interaction

This study identifies a parasitoid wasp species that suppresses Drosophila immune cell production by targeting the JNK signaling pathway.

Evolutionarily Conserved Transcription Factors Drive the Oxidative Stress Response in Drosophila

This study identifies conserved transcription factors regulating p38Kb expression in Drosophila, linking their activity to oxidative stress resistance.

G-OnRamp: Generating genome browsers to facilitate undergraduate-driven collaborative genome annotation

Galaxy-based platform builds UCSC Assembly Hubs, JBrowse and Apollo annotation browsers without bioinformatics expertise; parasitoid wasp browsers supported undergraduate research courses producing 192 gene models.