Author

A. Leal-Egana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Borkowetz· 1 shared A. Buehler· 1 shared A. Choudhury· 1 shared A. Dubrovska· 1 shared A. K. Bosserhoff· 1 shared A. Linge· 1 shared A. R. Boccaccini· 1 shared A. S. Köseer· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Borkowetz

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Author profile →

2 papers

Recent·Most cited

Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

I. Gorodetska, V. Lukiyanchuk, M. Gawin, M. Sliusar, A. Linge, F. Lohaus, T. Hölscher, K. Erdmann, S. Fuessel, A. Borkowetz, M. Reardon, A. Choudhury, Y. Antonelli, A. Leal-Egana, A. S. Köseer, , A. Dubrovska

This study identifies MMP11 as a blood-based biomarker for prostate cancer progression, regulated by the ALDH1A1-TGF-β1 signaling pathway.

Journal of Experimental & Clinical Cancer Research · Mar 24, 2025Peer-reviewedCancer Biology

When Mechanical Stress Matters: Generation of Polyploid Giant Cancer Cells in Tumor-like Microcapsules

A. Buehler, R. Krueger, M. Monavari, M. Fuentes-Chandia, R. Palmisano, J. Schoedel, A. R. Boccaccini, A. K. Bosserhoff, M. Kappelmann-Fenzl, G. Letort, A. Leal-Egana

This study shows that 3D environments induce polyploid cancer cells through mechanical stress and confinement, while 2D environments do not.

bioRxiv · Sep 22, 2022 · PreprintBioengineering