Author

G. Letort

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 5 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

A. Eichmuller· 2 shared C. Da Silva· 2 shared M. Thery· 2 shared M.-E. Terret· 2 shared M.-H. Verlhac· 2 shared A. Al Jord· 1 shared A. Buehler· 1 shared A. Chedotal· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

A. Eichmuller

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

When Mechanical Stress Matters: Generation of Polyploid Giant Cancer Cells in Tumor-like Microcapsules

A. Buehler, R. Krueger, M. Monavari, M. Fuentes-Chandia, R. Palmisano, J. Schoedel, A. R. Boccaccini, A. K. Bosserhoff, M. Kappelmann-Fenzl, G. Letort, A. Leal-Egana

This study shows that 3D environments induce polyploid cancer cells through mechanical stress and confinement, while 2D environments do not.

bioRxiv · Sep 22, 2022 · PreprintBioengineering

The filipodia-like protrusions of adjacent somatic cells shape the developmental potential of mouse oocytes

F. Crozet, G. Letort, C. Da Silva, A. Eichmuller, A. F. Tortorelli, M. Belle, J. Dumont, T. Piolot, A. Dauphin, F. Coulpier, A. Chedotal, J.-L. Maitre, M.-H. Verlhac, H. Clarke, M.-E. Terret

This study shows that TZPs, formed by Myosin-X, support oocyte-matrix integrity and gene expression, affecting mouse fertility.

bioRxiv · Sep 15, 2022 · PreprintCell Biology

Cytoplasmic forces functionally reorganize nuclear condensates in oocytes

A. Al Jord, G. Letort, S. Chanet, F.-C. Tsai, C. Antoniewski, A. Eichmuller, C. Da Silva, J.-R. HUYNH, N. Gov, R. Voituriez, M.-E. Terret, M.-H. Verlhac

This study shows that cytoplasmic forces reorganize nuclear condensates in oocytes, affecting mRNA processing and meiotic divisions.

bioRxiv · Mar 15, 2021 · PreprintCell Biology

Acto-myosin network geometry defines centrosome position

A. J. Jimenez, C. de Pascalis, G. Letort, B. Vianay, R. Goldman, M. Bornens, M. Piel, L. Blanchoin, M. Thery

This study shows that centrosome positioning is determined by actin network geometry rather than cell shape, with dynein forces placing the centrosome in an inner zone defined by actin contraction.

bioRxiv · Jan 7, 2020Cell Biology

Chromosomes function as a barrier to mitotic spindle bipolarity in polyploid cells

A. Goupil, M. Nano, G. Letort, D. Gogendeau, C. Pennetier, R. Basto

This study investigates how increased DNA and centrosome content in polyploid cells leads to mitotic spindle multipolarity and chromosomal instability.

bioRxiv · Mar 9, 2019Cell Biology

Microtubule stabilization drives 3D centrosome migration to initiate primary ciliogenesis

A. Pitaval, F. Senger, G. Letort, X. Gidrol, J. Sillibourne, M. THERY

This study identifies microtubule stabilization and cytoskeletal remodeling as key drivers of centrosome migration to initiate primary ciliogenesis.

bioRxiv · May 18, 2017Cell Biology