Cyclopamine sensitizes Glioblastoma cells to Temozolomide treatment through Sonic Hedgehog pathway
G. Basile Carballo, D. Matias, J. Honorato, L. Santos Pessoa, A. M. A. Neto, T. C. L. d. S. e. Spohr
This study shows cyclopamine enhances temozolomide's effect on glioblastoma cells by inducing apoptosis but also increases stemness markers like SOX-2 and OCT-4.
Life Sciences · Sep 1, 2020Peer-reviewedCancer Biology