Discovery, optimization, and cellular activities of 2-(aroylamino)cinnamamide derivatives against colon cancer
R. S. Elhaggar, A. M. Omar, M. K. Safo, T. A. Abdelghany, M. H. Ahmed, R. Boothello, B. B. Patel, M. S. Abdel-Bakky, A. M. Malebari, M. E. El-Araby
This paper discovers and optimizes 2-(aroylamino)cinnamamide derivatives that selectively kill colon cancer cells through apoptosis and oxidative stress, with minimal toxicity to normal cells.
bioRxiv · Dec 15, 2019 · PreprintCancer Biology