The genetic status of IDH1/2 and EGFR dictates the vascular landscape and the progression of gliomas
B. Segura-Collar, M. Garranzo-Asensio, B. Herranz, E. Hernandez-SanMiguel, B. S. Casas, A. Matheu, A. Perez-Nunez, J. M. Sepulveda-Sanchez, A. Hernandez-Lain, V. Palma, R. Gargini, P. Sanchez-Gomez
This study investigates how IDH1/2 and EGFR genetic mutations influence vascular characteristics and progression in gliomas, identifying distinct vascular phenotypes and therapeutic vulnerabilities.
bioRxiv · Sep 21, 2020 · PreprintCancer Biology