Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis
M. Alvarez-Martinez, L. S. Cox, C. F. Pearson, W. J. Branchett, P. Chakravarty, X. Wu, H. Slawinski, A. Al Dibouni, V. Samelis, L. Gabrysova, S. L. Priestnall, A. Suarez-Bonnet, A. Mikolajczak, J. Briscoe, F. Powrie, A. O'Garra
This study shows Blimp-1 and c-Maf regulate gene networks in T cells to prevent colitis, with distinct roles in controlling inflammatory pathways in mouse models.
bioRxiv · Sep 14, 2023 · PreprintImmunology