Signal Peptide of HIV-1 Envelope Functions to Modulate Glycosylation Impacting Exposure of V1V2 Epitopes
C. Upadhyay, R. Feyznezhad, L. Cao, K.-W. Chan, K. Liu, W. Yang, H. Zhang, J. Yolitz, J. Arthos, A. Nadas, X.-P. Kong, S. Zolla-Pazner, C. E. Hioe
This study shows that HIV-1 signal peptide diversity affects Env glycosylation and antibody recognition of V1V2 epitopes.
PLOS Pathogens · Dec 28, 2020Peer-reviewedMicrobiology