Spatially resolving how phosphorylation affects β-cardiac myosin activity in porcine myofibril sarcomeres with single molecule resolution
M. Pilagov, S. Steczina, A. Naim, M. Regnier, M. Geeves, N. M. Kad
This study uses single molecule imaging to analyze how phosphorylation affects myosin activity and cardiac reserve in porcine sarcomeres, identifying distinct kinetic states and their modulation by phosphorylation.
bioRxiv · Jun 27, 2024 · PreprintBiophysics