N. M. Kad

Combining cancer chemotherapeutics with bacterial DNA repair inhibitors to develop novel antimicrobials

This study combines cancer chemotherapeutics with bacterial DNA repair inhibitors to develop novel antimicrobials effective against multi-drug resistant E. coli.

Culture media, DMSO and efflux affect the antibacterial activity of cisplatin and oxaliplatin

This study shows that DMSO and growth media components like sulphur-containing amino acids reduce the antibacterial activity of cisplatin and oxaliplatin.

Single molecule imaging reveals the collective and independent search mechanisms of cFos and cJun on DNA

This study uses single molecule imaging to reveal that cFos and cJun use collective and independent search mechanisms to bind DNA, with cFos capable of independent DNA binding as monomers and homodimers.

The TFIIH subunits p44/p62 act as a damage sensor during nucleotide excision repair

This study shows that the TFIIH subunits p44 and p62 form a heterodimer that detects DNA damage during nucleotide excision repair.

Single molecule imaging reveals the concerted release of myosin from regulated thin filaments

The paper uses single molecule imaging to show that myosin detachment from thin filaments occurs in a coordinated, active process during deactivation.