Author

A. O. Smirnova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Research Focus:batch correction / integration· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. M. Miroshnichenkova· 2 shared A. Y. Komkov· 2 shared D. M. Chudakov· 2 shared Y. B. Lebedev· 2 shared I. Mamedov· 1 shared I. V. Kelmanson· 1 shared I. Z. Mamedov· 1 shared L. D. Belyaeva· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. M. Miroshnichenkova

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2 papers

Recent·Most cited

Non-canonical D1-D2 recombination produces two types of rearrangements and represents a conservative hidden stage of T-cell receptor beta chain generation

A. O. Smirnova, A. M. Miroshnichenkova, L. D. Belyaeva, I. V. Kelmanson, Y. B. Lebedev, I. Z. Mamedov, D. M. Chudakov, A. Y. Komkov

The paper identifies non-canonical D1-D2 recombination in T-cell receptor beta chain generation, revealing two types of rearrangements and their role in memory T-cell function.

bioRxiv · Apr 21, 2023 · PreprintImmunology

The use of non-functional clonotypes as a natural calibrator for quantitative bias correction in adaptive immune receptor repertoire profiling

A. O. Smirnova, A. M. Miroshnichenkova, Y. V. Olshanskaya, M. A. Maschan, Y. B. Lebedev, D. M. Chudakov, I. Mamedov, A. Y. Komkov

The paper introduces a method to correct PCR bias in immune repertoire sequencing by using non-functional clonotypes as a calibrator, improving accuracy across different sequencing approaches.

bioRxiv · Mar 24, 2021Immunology