Rescue of aged muscle stem cell quiescence defects by AKT inhibition revealed with a 3D biomimetic culture assay
E. Jacques, Y. Kuang, A. P. Kann, R. S. Krauss, P. M. Gilbert
This paper develops a 3D biomimetic culture assay to study muscle stem cell quiescence and shows that AKT inhibition rescues quiescence defects in aged cells.
bioRxiv · Jun 15, 2022Bioengineering