Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates
A. P. Latham, L. Zhu, D. A. Sharon, S. Ye, A. P. Willard, X. Zhang, B. Zhang
This study uses simulations and experiments to show that diblock polypeptides form interfacial environments due to hydrophilic-hydrophobic residue distribution, affecting condensate stability and hydrogen bonding.
bioRxiv · Mar 30, 2023Biophysics